2025Year

Second Semester

Advanced Study on Bioactive Molecules Chemistry

Lecture

Advanced Study on Bioactive Molecules Chemistry

Z1900039 Advanced Study on Bioactive Molecules Chemistry

OHNO Osamu

2.0Credits

Tue.2Period

Hachioji Campus

1W-027講義室

A) A high degree of specialized expertise　100%
B) The skills to use science and technology　0%
C) The ability to conduct research independently, knowledge pertaining to society and occupations, and sense of ethics required of engineers and researchers　0%
D) Creative skills in specific areas of specialization　0%

Almost all organic compounds contained in living organisms have some role in carrying out life activities. Some of them show peculiar effects in extremely small amounts in development, differentiation, growth, reproduction, and homeostasis. These are collectively called bioactive substances. In this lecture, we will learn about the history, chemical structure, biosynthesis, mechanism of action, and application of various bioactive substances discovered from nature. In particular, we will explain historically important bioactive substances and bioactive substances discovered in the latest research, along with specific research cases. Through this lecture, I aim to lecture how to understand the molecules that govern life phenomena from the perspectives of organic chemistry and life science.

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Other／Not used

1st
Basics of bioactive substances
Flow of bioactive substance research
2nd
Bio assay methods
3rd
Purification and isolation of biologically active substances①
4th
Purification and isolation of biologically active substances②
5th
History of bioactive substance research
An important bioactive substance that colors history
6th
Bioactive substances seen from biosynthesis ①
Major biosynthetic pathways
7th
Bioactive substance seen from biosynthesis ②
Fatty acids and related compounds
Polyketide and related compounds
8th
Bioactive substance seen from biosynthesis ③
Terpenoids and related compounds
Alkaloids and related compounds
Peptides and related compounds
9th
Endogenous biologically active substance from the viewpoint of function
Hormone, Growth factors, Pheromones
10th
Extrinsic xenobiotic substance from the viewpoint of function ①
Plant growth regulator
Plant-derived pharmacologically active substances
vitamin
Nutrients
11th
Extrinsic xenobiotic substance from the viewpoint of function ②
Antibiotics
Cell function regulator
Enzyme inhibitor
Biological poison
Fluorescent and luminescent compounds
12th
Development of bioactive substance chemistry ①
Hormone receptors and mechanism of action
New screening system
13th
Development of bioactive substance chemistry ②
Expansion into chemical biology
Advances in genomics and comprehensive analysis technology and their impact
14th
Review

Quizzes to confirm comprehension will be conducted in the lesson, a normal score will be calculated, and a report related to the lesson content will be imposed after all the lectures (normal score: report = 6: 4).

Face-to-face and remote commentary is provided during class hours and outside business hours.

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Nothing.

Office hours: Tuesday 13:30 to 15:00
Location: Room 12-111
I recommend that you contact me before asking.
Email address: st13515@ns.kogakuin.ac.jp

In this lecture, I will lecture the history, chemical structure, biosynthesis, mechanism of action, and application, focusing on bioactive substances discovered from nature. Through this lecture, I hope that you will deepen your understanding of the molecules that govern life phenomena from the perspectives of organic chemistry and life science.

Not applicable

Not applicable